VES DIGITAL ACADEMY

• Course Name: Drug Discovery –

  Course Objective : 

  1. To know the basics and requirements of computational chemistry and applications in Drug discovery
  2. To understand and apply quantum chemistry principles to drug discovery problems
  3. To understand the principle and application and apply it for the design of drug candidate
  4. To understand, apply, create, and analyze the homology model. 
  5. To understand, apply, create, and analyze the QSAR equations. 
  6. To understand, apply, create, and analyze the pharmacophore models.
• Course Name: Optimiztion Techniques –

  Course Objective: 

  • To learn the fundamentals of optimization-process/ method/ formulation optimization
  • To learn various optimization design and its application
  • To learn software used for optimization
• Course Name: Academic Research Writing –

  Course Objective: 

  This course aims to enable the students:

  • To practice the basic skills of performing quality literature review.
  • To differentiate between various kinds of academic writings.
  • To practice the basic skills of research paper, review paper and thesis writing.
  • To identify and avoid plagiarism.
  • To target the research work to suitable journal and communicate for publication.
• Course Name: Analytical Chemistry –

  Course Objectives: 

  • To provide a step-by-step approach to method development by UV-Visible spectroscopy and reverse phase HPLC
  • To enable implementation of systematic and efficient approach to method development by UV-Visible spectroscopy and reverse phase HPLC

• Drug Discovery

Course Duration : 1 Months (12 hrs)

Course Fees : 2,000/-

Certification : Certified by VES College of Pharmacy

• Optimiztion Techniques

Course Duration : 1 Months (8 hrs)

Course Fees : 2,000/-

Certification : Certified by VES College of Pharmacy

• Academic Research Writing

Course Duration : 1 Months (5 hrs)

Course Fees : 1,000/-

Certification : Certified by VES College of Pharmacy

• Analytical Chemistry

Course Duration : 1 Months (12 hrs)

Course Fees : 2,000/-

Certification : Certified by VES College of Pharmacy

Optimizations Techniques – Course Syllabus

Modules:

1. Optimization techniques and fundamentals

   Formulation: Concept and parameters of

   optimization

2. Different types of Optimization techniques, Statistical design, Response surface method, Contour designs
3. Factorial designs and applications with case studies
4. Software for designs and Optimization

Reference Material:

1. Drugs and the Pharmaceutical Sciences, Banker,Modern Pharmaceutics-CRC Press (2002).
2. Pharmaceutical Statistics: Practical and Clinical Applications by  Sanford Bolton, Charles Bon
3. “Design of Experiments: Statistical Principles of Research Design and Analysis” by Robert O Kuehl
4. Statistical Design and Analysis of Experiments: With Applications to Engineering and Science

by Robert L. Mason, Richard F. Gunst, James L. Hess

1. Design-Expert® software- https://www.statease.com/docs/v13/

Academic Research Writing- Course Syllabus

Modules:

1. Tools for Effective Literature Review (1 hour)

   1. Understanding the Literature Review Process
      1. Overview of the literature review process and its importance in research
      2. Different types of literature reviews (narrative, systematic, scoping, meta-analysis)
   2. Developing a Literature Search Strategy
      1. Identifying relevant search terms and keywords
      2. Choosing appropriate databases and search engines
      3. Techniques for refining search results and avoiding bias
   3. Critical Reading and Evaluation of Literature
      1. Strategies for evaluating the quality and relevance of research articles
      2. Assessing the credibility and reliability of sources
      3. Identifying gaps in existing literature and potential research opportunities
   4. Efficiently Reading and Annotating Literature
      1. Techniques for efficient reading and note-taking
      2. Best practices for annotating articles and organizing notes
      3. Tools for facilitating efficient literature review (e.g., summarization software, annotation apps)

2. Strategies of academic writing (2 hours)

   1. Academic Writing Style and Tone:
      1. Establishing a professional and academic writing style.
      2. Understanding audience expectations and needs.
      3. Developing an appropriate writing tone.
   2. Writing the Introduction:
      1. Crafting a strong thesis statement.
      2. Providing context and background information.
      3. Defining key terms and concepts.
   3. Methods and Materials:
      1. Describing the research design and methods.
      2. Detailing data collection and analysis procedures.
      3. Addressing ethical considerations.
   4. Results:
      1. Organizing and presenting research findings.
      2. Using tables, charts, and graphs to display data.
      3. Interpreting and analyzing research results.
   5. Discussion and Conclusion:
      1. Interpreting research results and discussing implications.
      2. Addressing research limitations and future directions.
      3. Crafting a strong conclusion that highlights key findings.

3. Referencing Styles and managers & Plagiarism Check

   1. Overview of popular citation management tools (e.g., Zotero, Mendeley, EndNote).
   2. Organizing and managing references.
   3. Creating and formatting bibliographies and in-text citations.
   4. Paraphrasing and plagiarism check tools.

4. The Art of Journal Selection

   1. Understanding the academic publishing landscape: An overview of the academic publishing landscape, including the different types of journals, open access publishing, and predatory journals.
   2. Identifying potential target journals: How to identify potential target journals for your research paper, including databases and search engines that can help with the process.
   3. Analyzing the journal’s scope and focus: How to analyze the scope and focus of a journal to determine whether it is a good fit for your research.
   4. Assessing the journal’s quality and impact: How to assess the quality and impact of a journal using metrics such as impact factor, citation analysis, and indexing in databases.
   5. Understanding the submission process: An overview of the journal submission process, including manuscript formatting, submission guidelines, and author guidelines.
   6. Managing the review process: How to manage the peer review process, including responding to reviewer comments and revising your manuscript.
   7. Addressing ethical issues: An overview of ethical issues in academic publishing, including plagiarism, authorship, and conflicts of interest.
   8. Selecting the best fit journal: A step-by-step guide to selecting the best fit journal for your research paper based on the above factors.

References

1. “A Handbook of Critical Approaches to Literature” by Wilfred L. Guerin, Earle Labor, Lee Morgan, and Jeanne C. Reesman
2. “Systematic Approaches to a Successful Literature Review” by Andrew Booth, Anthea Sutton, and Diana Papaioannou
3. “Critical Reading and Writing for Postgraduates” by Mike Wallace and Alison Wray
4. https://quillbot.com/summarize
5. “Research Methods in Education” by Louis Cohen, Lawrence Manion, and Keith Morrison
6. “How to Write and Publish a Scientific Paper” by Robert A. Day and Barbara Gastel
7. https://www.zotero.org/support/quick_start_guide
8. https://www.mendeley.com/guides
9. https://www.turnitin.com/
10. https://quillbot.com/
11. Suiter AM, Sarli CC. Selecting a Journal for Publication: Criteria to Consider. Mo Med. 2019 Nov-Dec;116(6):461-465.
12. Bavdekar, Sandeep. (2015). Choosing the Right Journal for a Scientific Paper. The Journal of the Association of Physicians of India. 63. 56.

Analytical Chemistry – Course Syllabus

Course Modules: 

1. Basics of UV-Visible spectrophotometer Instrumentation

• Basic components of uv-visible spectrophotometer- Light source, wavelength selectors, sample holder, detectors, cuvettes
• Commercially available uv-visible spectrophotometers 

  2. Practical aspects of method development by UV-Visible spectroscopy

• • Selection of medium/solvent
  • Selection of detection wavelength
• Analysis of samples in presence of sample matrix

3. Basics of HPLC Instrumentation

• Basic components of an HPLC- Mobile phase reservoirs, pumps, columns, sample injection systems, detectors, data acquisition systems, tubes & fittings
• Specific emphasis on instrumentation of RP-HPLC with UV detection
• Commercially available HPLC equipments

4. Principle of separation in RP-HPLC

• Introduction to Resolution. The concepts of efficiency, retention factor and selectivity. The way to optimize each parameter and its role in reversed-phase resolution is explained.
• Reversed-Phase HPLC Columns and their characteristics
• The matrix and the nature of the stationary phase
• How hydrophobic, polar and ionic interactions contribute to and affect reversed-phase retention and selectivity.
• The type of stationary phases available and how each affects selectivity.

5. Principle of separation by RP-HPLC

• How to evaluate and compare columns in order to select the best column for a given separation.
• Reversed-Phase HPLC Mobile Phases and their characteristics.
• How to find the best solvent concentration for a method
• How solvent type and concentration affects selectivity and why
• How the pH of the mobile phase is used to optimize the separation of basic and acidic compounds.
• Temperature. The affect of column temperature on retention and selectivity is described.
• An overview of type of elution-isocratic Vs gradient

Requirements:  

Notebook, access to internet

Virtual Demonstration of Handling & Operation

1. Handling, operation and troubleshooting of UV-Visible spectroscopy

   Expert: Dr. Anita Ayre & Ms. Palak Karia

2. Handling, operation and troubleshooting of HPLC

   Expert: Dr. Anita Ayre & Ms. Palak Karia

Reference Books:

1. Text book of Pharmaceutical Analysis by Kenneth A. Connors 
2. Vogel‘s Text book of Quantitative  Chemical Analysis by A.I. Vogel
3. Instrumental Methods of Analysis by Skoog
4. Practical Pharmaceutical Chemistry by A.H. Beckett and J.B. Stenlake
5. HPLC Method Development by Snyder & Kirkland

Drug Discover Syllabus 

Science & Technology

Academic Research Writing Dr. Anand Chintakrindi Designation: Assistant Professor Name of Institute: Vivekanand Education Society’s College of Pharmacy Qualification: Ph. D. (Tech.) in Pharmaceutical Chemistry	Analytical Chemistry Dr. Anita Ayre Designation: Associate Professor Name of Institute: Vivekanand Education Society’s College of Pharmacy Qualification: Ph. D. (Tech.) in Pharmaceutical Chemistry	Optimization Techniques Dr (Mrs.) Supriya Shrihari Shidhaye Designation: Principal and Professor Name of Institute: Vivekanand Education Society’s College of Pharmacy Qualification: Ph.D (Tech) in Pharmaceutics

Drug Discovery Dr. Mushtaque Shaikh Designation: Associate Professor Name of Institute: Vivekanand Education Society’s College of Pharmacy Qualification: Ph. D. (Tech.) in Pharmaceutical Chemistry	Optimization Techniques Ms. Shivali Tank Designation: Ph.D. Scholar/ Assistant Professor Name of Institute: Vivekanand Education Society’s College of Pharmacy Qualification: M.Pharm in Pharmaceutics

For any queries, contact us at:

Email: vesda@ves.ac.in

Mobile No: 9004856754